Book: Molecular Imaging: An Essential Tool in Preclinical Research, Diagnostic Imaging, and Therapy (Ernst Schering Foundation Symposium Proceedings)
ISBN: 9783540210214
Publisher: Springer
Year: 2004
"Molecular imaging" has been previously defined as "the in vivo
characterization and measurement of biologic processes at the cellu
lar and molecular level." This broad definition emerged during the
last few years as a consequence of the convergence of molecular and
cell biology with imaging science, including medical physics and
technology. One of the major goals of molecular imaging has be
come the development of noninvasive strategies of "molecular profil
ing" in living subjects, i.e., the acquisition and analysis of maps re
flecting the spatial and temporal distribution of a given molecular
target at a precise anatomical location without biopsies. The map
ping of disease-relevant gene expression profiles in vivo would be
especially important for individualizing established therapy regimens
in clinical practice and selecting patients for novel experimental
therapies.
The continuous progress in the understanding of molecular processes of disease formation and progression attributes an increasing importance to biomedical molecular imaging methods. The purpose of this workshop was to discuss and overview multiple applications and emerging technologies in the area of diagnostic imaging including its fundamental capabilities in preclinical research, the opportunities for medical care, and the options involving therapeutic concepts. The book provides the reader with state-of-the-art information on the different aspects of diagnostic imaging, illuminating new developments in molecular biology, imaging agents and molecular probe design, and therapeutic techniques.
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